Main Street Hyannis Hotels

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Looking for a hotel on Main Street in Hyannis?  Enter your travel dates to compare available hotels on Main Street Hyannis only or browse the list below to see all hotels found on Main Street Hyannis. If you do wish to see a wider view of Hyannis then please select 'All' Hyannis hotels when you select your dates.  Please also see the map showing just the hotels along Main Street Hyannis.

2.5 star
259 Main Street Hyannis 02601
1.45 km from Hyannis HYA-Barnstable Municipal airport

Heritage House Hotel is in the heart of Hyannis, walking distance from John F. Kennedy Hyannis Museum and Cape Cod Baseball Hall of Fame. This hotel is within close proximity of Hyannis Harbor and St....more


Rated 3.5 out of 5 by 45
2.5 star
662 Main Street Hyannis 02601
2.06 km from Hyannis HYA-Barnstable Municipal airport

International Inn is in the heart of Hyannis, walking distance from Cape Cod Carousel and St. Francis Xavier Church. This romantic hotel is within close proximity of Cape Cod Melody Tent and Twin Broo...more


Rated 2.5 out of 5 by 602
3 star
473 Main Street Hyannis MA 02601
1.72 km from Hyannis HYA-Barnstable Municipal airport

Located in Cape Cod, this Main Street inn offers free WiFi and traditionally decorated rooms equipped with a flat-screen TV and a mini-refrigerator. The John F. Kennedy Hyannis Museum is within walkin...more

Superb 9.1/10
Score from 526 reviewers
3 star
662 Main Street Hyannis MA 02601
2.06 km from Hyannis HYA-Barnstable Municipal airport

International Inn is located in Hyannis, 1.6 km from the ferry to Martha's Vineyard and Nantucket. Guests can enjoy the on-site restaurant and bar. Certain units have a seating area. The rooms are fit...more

Review score 6.4/10
Score from 315 reviewers
3 self rated
259 Main Street Hyannis MA 02601
1.46 km from Hyannis HYA-Barnstable Municipal airport

Steps from scenic Hyannis Harbor as well as ferries leading to Martha's Vineyard, this solar-powered hotel features with guestrooms offering free WiFi and FREE parking. The Heritage House Hotel is ide...more

Good 7.3/10
Score from 461 reviewers
2 self rated
447 Main Street Hyannis MA 02601
1.66 km from Hyannis HYA-Barnstable Municipal airport

Centrally located on Main Street in Hyannis city centre, this hotel is a short walk from the scenic waterfront of Cape Cod. Stop by for a pleasant and memorable stay. A complimentary continental break...more


Rated 3.5 out of 5 by 147
2 star
206 Main Street Hyannis MA 02601
1.44 km from Hyannis HYA-Barnstable Municipal airport

Located just 650 metres from the harbor and ferry service to Nantucket, this Hyannis hotel features indoor and outdoor pools. Free Wi-Fi and a continental breakfast are provided. The spacious rooms of...more

Good 7.5/10
Score from 868 reviewers
460 Main Street Hyannis 02601

Featuring barbecue facilities and a restaurant, Courtyard Resort is located in Hyannis. 3.5 km from Cape Cod Beer Brewery, the property is also 2 minutes' from John F Kennedy Hyannis Museum. St Franci...more

Good 7.2/10
Score from 22 reviewers
3 star
657 West Main Street Hyannis MA 02601
3.20 km from Hyannis HYA-Barnstable Municipal airport

Located just 1-mile from Craigville Beach, this resort offers suites with a kitchen. An indoor swimming pool and a hot tub are available on-site.A microwave and a fridge are included in each light and...more


Rated 3.5 out of 5 by 31



Last updated: 14 Nov 2019

Book now and pay later rooms are subject to availabilty.

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